DTX2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5109664-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5109664 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
DTX2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DTX2
Gene Alias
2610524D08Rik; AA408415; AU022494; deltex 2 homolog; deltex 2 homolog (Drosophila); deltex 2, E3 ubiquitin ligase; deltex E3 ubiquitin ligase 2; deltex homolog 2; deltex2; Dtx2; hDTX2; KIAA1528; mDTX2; probable E3 ubiquitin-protein ligase DTX2; Protein deltex-2; ring finger protein 58; RING-type E3 ubiquitin transferase DTX2; RNF58; zinc ion binding protein
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
113878, 304591, 74198
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.34 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q86UW9, Q8R3P2
Gene Symbols
DTX2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human DTX2 (NP_065943.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MAMAPSPSLV QVYTSPAAVA VWEWQDGLGT WHPYSATVCS FIEQQFVQQK GQRFGLGSLA HSIPLGQADP SLAPYIIDLP SWTQFRQDTG TMRAVRRHLF PQHSAPGRGV VWEWLSDDGS WTAYEASVCD YLEQQVARGN QLVDLAPLGY NYTVNYTTHT QTNKTSSFCR SVRRQAGPPY PVTTIIAPPG HTGVACSCHQ CLSGSRTGPV SGRYRHSMTN LPAYPVPQHP PHRTASVFGT HQAFAPYNKP SLSGARSAPR LNTTNAWGAA PPSLGSQPLY DTX2 functions as an E3 ubiquitin ligase
- Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations
- Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context
- Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1
- Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.