CBX4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5109482-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA5109482 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
CBX4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CBX4
Gene Alias
Cbx4; chromobox 4; chromobox homolog 4; chromobox homolog 4 (Pc class homolog, Drosophila); chromobox protein homolog 4; chromobox-like protein 4; E3 SUMO-protein ligase CBX4; E3 SUMO-protein transferase CBX4; hPc2; MPc2; NBP16; NS5ATP1-binding protein 16; Pc class 2 homolog; PC2; Polycomb 2 homolog
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12418, 8535
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.69 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O00257, O55187
Gene Symbols
CBX4
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 401-560 of human CBX4 (NP_003646.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AVGLNLSHVR KRCLSETHGE REPCKKRLTA RSISTPTCLG GSPAAERPAD LPPAAALPQP EVILLDSDLD EPIDLRCVKT RSEAGEPPSS LQVKPETPAS AAVAVAAAAA PTTTAEKPPA EAQDEPAESL SEFKPFFGNI IITDVTANCL TVTFKEYVTV Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance
- At least two distinct human PcG complexes have been identified
- Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1)
- CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins
- It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation
- Depletion of CBX4 results in decreased cellular resistance to ionizing radiation
- CBX4 is directly involved in the cellular response to DNA damage.