LGP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5109635-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5109635 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
LGP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DHX58
Gene Alias
B430001I08Rik; D11LGP2; D11lgp2e; DEXH (Asp-Glu-X-His) box polypeptide 58; DEXH-box helicase 58; DHX58; Lgp2; LPG2; ortholog of mouse D11lgp2; probable ATP-dependent helicase LGP2; Probable ATP-dependent RNA helicase DHX58; protein D11Lgp2; Protein D11Lgp2 homolog; RGD1310093; RIG-I-like receptor 3; RIG-I-like receptor Lgp2; RLR; RLR-3; RNA helicase LGP2
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
303538, 79132, 80861
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
2.08 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q96C10, Q99J87
Gene Symbols
DHX58
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 389-678 of human DHX58 (NP_077024.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: QQQGLQTVDI RAQLLIGAGN SSQSTHMTQR DQQEVIQKFQ DGTLNLLVAT SVAEEGLDIP HCNVVVRYGL LTNEISMVQA RGRARADQSV YAFVATEGSR ELKRELINEA LETLMEQAVA AVQKMDQAEY QAKIRDLQQA ALTKRAAQAA QRENQRQQFP VEHVQLLCIN CMVAVGHGSD LRKVEGTHHV NVNPNFSNYY NVSRDPVVIN KVFKDWKPGG VISCRNCGEV WGLQMIYKSV KLPVLKVRSM LLETPQGRIQ AKKWSRVPFS VPDFDFLQHC AENLSDLSLD Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms
- The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids
- Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm
- A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain
- It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling
- At least four isoforms of LGP2 are known to exist.