MID1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5109957-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5109957 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
MID1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MID1
Gene Alias
61B3-R; BBBG1; DXHXS1141; E3 ubiquitin-protein ligase Midline-1; Finger on X and Y (in rat only on X); Fxy; GBBB1; Mid1; Midin; midline 1; midline 1 (Opitz/BBB syndrome); midline 1 RING finger protein; Midline1; midline-1; OGS1; Opitz/BBB syndrome; OS; OSX; Putative transcription factor XPRF; RING finger protein 59; RING finger protein Midline-1; RING-type E3 ubiquitin transferase Midline-1; RNF59; TRIM18; tripartite motif protein TRIM18; tripartite motif-containing protein 18; XPRF; zinc finger on X and Y, mouse, homolog of; ZNFXY
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17318, 4281
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.54 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O15344, O70583
Gene Symbols
MID1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 478-667 of human MID1 (NP_000372.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: KLKTNSQPFK LDPKSAHRKL KVSHDNLTVE RDESSSKKSH TPERFTSQGS YGVAGNVFID SGRHYWEVVI SGSTWYAIGL AYKSAPKHEW IGKNSASWAL CRCNNNWVVR HNSKEIPIEP APHLRRVGIL LDYDNGSIAF YDALNSIHLY TFDVAFAQPV CPTFTVWNKC LTIITGLPIP DHLDCTEQLP Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1
- Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger
- Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation
- It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2
- It also interacts with IGBP1 (Lymphocyte signaling protein A4)
- Defects in MID1 are the cause of Opitz syndrome type I (OS-I)
- OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects.