PHIP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5110105-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA5110105 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
PHIP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PHIP
Gene Alias
2810004D21Rik; 4632404O06Rik; BRWD2; DCAF14; DDB1 and CUL4 associated factor 14; DDB1- and CUL4-associated factor 14; FLJ20705; IRS-1 PH domain-binding protein; Ndrp; neuronal differentiation related protein; neuronal differentiation-related protein; PH-interacting protein; PHIP; pleckstrin homology domain interacting protein; WD repeat domain 11; WD repeat-containing protein 11; WDR11
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
55023, 83946
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.203 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q8VDD9, Q8WWQ0
Gene Symbols
PHIP
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1542-1821 of human PHIP (NP_060404.3).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: KTILENSVKH SKALNTLSSP GQSSFSHGTR NNSAKENMEK EKPVKRKMKS SVLPKASTLS KSSAVIEQGD CKNNALVPGT IQVNGHGGQP SKLVKRGPGR KPKVEVNTNS GEIIHKKRGR KPKKLQYAKP EDLEQNNVHP IRDEVLPSST CNFLSETNNV KEDLLQKKNR GGRKPKRKMK TQKLDADLLV PASVKVLRRS NRKKIDDPID EEEEFEELKG SEPHMRTRNQ GRRTAFYNED DSEEEQRQLL FEDTSLTFGT SSRGRVRKLT EKAKANLIGW PHIP (pleckstrin homology domain interacting protein), also known as ndrp or WDR11, is a 1,821 amino acid protein that contains eight N-terminal WD40 repeats and two bromodomains
- It is expressed in skeletal muscle (localizing to the cytosol and nucleus) and primary beta cells (localizing to the nucleus) and acts as a transcriptional activator
- PHIP is known to interact with various members of the insulin receptor substrate (IRS) family
- The IRS family of proteins mediate insulin receptor signaling and play an important role in insulin-producing beta cell proliferation and survival
- PHIP specifically associates with the PH domain of IRS-1 and may function to link IRS-1 to insulin receptors, indicating a vital role of PHIP in the regulation of insulin signaling.