PIPA5110157

Phospho-STAT6 (Tyr641) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5110157-Each-of-1 In Stock ₹ 46,502.50

PIPA5110157 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-STAT6 (Tyr641)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

STAT6

Gene Alias

12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20852, 362896, 6778

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

2.08 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.

P42226, P52633

Gene Symbols

STAT6

Immunogen

A synthetic phosphorylated peptide around Y641 of human STAT6 (NP_0031443)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RGYVP STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13
  • (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation
  • STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta
  • STAT6 is critically involved in Th2 immune response
  • STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.