Phospho-SP1 (Thr739) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104771-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA5104771 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
Phospho-SP1 (Thr739)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SP1
Gene Alias
1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20683, 24790, 6667
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O89090, P08047, Q01714
Gene Symbols
SP1
Immunogen
A synthesized peptide derived from human SP1(Accession P08047), corresponding to amino acid residues around phosphorylated Thr739.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of SP1 only when phosphorylated at Threonine 739
- SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli
- Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses
- Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation)
- Binds also the PDGFR-alpha G-box promoter
- May have a role in modulating the cellular response to DNA damage
- Implicated in chromatin remodeling
- Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter
- Plays an essential role in the regulation of FE65 gene expression.