PR3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5110224-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA5110224 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
PR3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PRTN3
Gene Alias
ACPA; AGP7; azurophil granule protein 7; CANCA; C-ANCA; C-ANCA antigen; leukocyte proteinase 3; MBN; MBT; mPR3; Myeloblastin; neutrophil proteinase 4; NP4; NP-4; P29; PR3; PR-3; Proteinase 3; PRTN3; serine proteinase, neutrophil; wegener autoantigen; Wegener granulomatosis autoantigen
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
314615
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.75 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
0
Gene Symbols
PRTN3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 28-170 of human Proteinase 3/PR3 (NP_0027683)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: IVGGHEAQPH SRPYMASLQM RGNPGSHFCG GTLIHPSFVL TAAHCLRDIP QRLVNVVLGA HNVRTQEPTQ QHFSVAQVFL NNYDAENKLN DVLLIQLSSP ANLSASVATV QLPQQDQPVP HGTQCLAMGW GRVGAHDPPA QVL Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246)
- By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369)
- May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279)
- [UniProt]