PIPA5110817

KCNQ5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5110817-Each-of-1 In Stock ₹ 48,905.50

PIPA5110817 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

KCNQ5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KCNQ5

Gene Alias

7730402H11; 9230107O05Rik; AA589396; D1Mgi1; KCNQ5; Kcnq5l; KQT-like 5; Kv7.5; KvLQT5; potassium channel protein; potassium channel subunit alpha KvLQT5; potassium channel, voltage gated KQT-like subfamily Q, member 5; potassium channel, voltage-gated KQT-like subfamily Q, member 5; potassium voltage-gated channel subfamily KQT member 5; potassium voltage-gated channel subfamily Q member 5; potassium voltage-gated channel, KQT-like subfamily, member 5; potassium voltage-gated channel, subfamily Q, member 5; rCG_43583; voltage-gated potassium channel subunit Kv7.5; voltage-gated potassium channel type Kv7.5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56479

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.10 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q9NR82

Gene Symbols

KCNQ5

Immunogen

Recombinant Protein corresonding to Human KCNQ5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: LALASFQIPP FECEQTSDYQ SPVDSKDLSG SAQNSGCLSR STSANISRGL QFILTPNEFS AQTFYALSPT MHSQATQVPI SQSDGSAVAA TNTIANQINT APKPAAPTTL QIPPPL KCNQs are members of the voltage-dependent non-inactivating potassium channel family
  • Currently there are five known KNCQs (KCNQ1-5) found in the central nervous system
  • Studies have shown that KCNQ3 and KCNQ5 form heteromultimers that, when formed, substantially increase the M-current
  • Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs
  • Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy
  • Voltage-dependent potassium channels are key regulators of the resting membrane potential and modulate the excitability of electrically active cells
  • The channels are usually tetrameric and can interact with auxiliary subunits that enhance or modify currents mediated by the pore-forming subunits.