PIPA5111246

Aquaporin 2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5111246-Each-of-1 In Stock ₹ 48,905.50

PIPA5111246 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

Aquaporin 2

Classification

Polyclonal

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P41181

Gene Symbols

Aqp2

Immunogen

Recombinant Protein corresonding to Human Aquaporin 2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry

Conjugate

Unconjugated

Gene

Aqp2

Gene Alias

ADH water channel; AQP 2; AQP CD; Aqp2; AQP-2; AQPCD; AQP-CD; aquaporin 2; aquaporin 2 (collecting duct); Aquaporin CD; Aquaporin2; aquaporin-2; Aquaporin-CD; Aquaporine 2; collecting duct water channel protein; cph; jpk; MGC34501; Water channel protein for renal collecting duct; water-channel aquaporin 2; WCH CD; WCHCD; WCH-CD

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

359

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Immunogen sequence: VLFPPAKSLS ERLAVLKGLE PDTDWEEREV RRRQSVELHS PQSL Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct
  • Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans
  • A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells
  • Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking.