USP8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5111308-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA5111308 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
USP8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
USP8
Gene Alias
AI574262; AW557536; Deubiquitinating enzyme 8; hUBPy; HumORF8; Kiaa0055; mKIAA0055; mUBPy; putative deubiquitinating enzyme; SPG59; Ubiquitin carboxyl-terminal hydrolase 8; ubiquitin isopeptidase Y; ubiquitin specific peptidase 8; ubiquitin specific protease 8; ubiquitin thioesterase 8; ubiquitin thiolesterase 8; ubiquitin-specific-processing protease 8; Ubpy; USP8
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9101
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry
Concentration
0.20 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P40818
Gene Symbols
USP8
Immunogen
Recombinant Protein corresonding to Human USP8
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: KRPDFKQQQD YFHSILGPGN IKKAVEEAER LSESLKLRYE EAEVRKKLEE KDRQEEAQRL QQKRQETGRE DGGTLAKGSL ENVLDSKDKT QKSNGEKNEK CETKEKGAIT AKELYTMMTD USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation
- USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1
- USP8 may regulate T-cell energy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2
- As revealed by structure/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1
- Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.