PIPA5112784

USP6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112784-Each-of-1 In Stock ₹ 43,476.50

PIPA5112784 - Each of 1

₹ 43,476.50

In Stock

Quantity

1

Base Price: ₹ 43,476.50

GST (18%): ₹ 7,825.77

Total Price: ₹ 51,302.27

Antigen

USP6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

USP6

Gene Alias

Deubiquitinating enzyme 6; HRP1; hyperpolymorphic gene 1; proto-oncogene TRE-2; TBC1D3 and USP32 fusion; TRE17; TRE2; Tre-2; TRESMCR; Ubiquitin carboxyl-terminal hydrolase 6; ubiquitin specific peptidase 6; ubiquitin specific peptidase 6 (Tre-2 oncogene); ubiquitin specific protease 6 (Tre-2 oncogene); ubiquitin thioesterase 6; ubiquitin thiolesterase 6; ubiquitin-specific protease USP6; ubiquitin-specific-processing protease 6; USP6; USP6-short

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

9098

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

2.85 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

P35125

Gene Symbols

USP6

Immunogen

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 6 protein (1122-1359AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety
  • It catalyzes its own deubiquitination
  • In vitro, isoform2, but not isoform3, shows deubiquitinating activity
  • USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking
  • It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.