CASC3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5111310-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA5111310 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
CASC3
Classification
Polyclonal
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
O15234
Gene Symbols
CASC3
Immunogen
Recombinant Protein corresonding to Human CASC3
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry
Conjugate
Unconjugated
Gene
CASC3
Gene Alias
Barentsz; barentsz protein; BTZ; cancer susceptibility candidate 3; cancer susceptibility candidate gene 3 protein; Cancer susceptibility candidate gene 3 protein homolog; Casc3; mBtz; metastatic lymph node 51; metastatic lymph node gene 51 protein; Metastatic lymph node gene 51 protein homolog; MLN 51; MLN 51 homolog; Mln51; Protein barentsz; protein CASC3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22794
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Immunogen sequence: DSEGEEGEYS EEENSKVELK SEANDAVNSS TKEEKGEEKP DTKSTVTGER QSGDGQESTE PVENKVGKKG PKHLDDDEDR KNPAYIPRKG LFFEHDLR The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator
- The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits
- The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits
- Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway
- An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides
- The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator
- Three subunits of the 11S regulator have been identified
- This gene encodes the gamma subunit of the 11S regulator
- Six gamma subunits combine to form a homohexameric ring
- Two transcript variants encoding different isoforms have been identified.