TMC6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5111336-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA5111336 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
TMC6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TMC6
Gene Alias
D11Ertd204e; epidermodysplasia verruciformis 1; epidermodysplasia verruciformis protein 1; EV1; EVER1; EVIN1; expressed in activated T/LAK lymphocytes; LAK-4P; protein LAK-4; Tmc6; transmembrane channel like 6; transmembrane channel-like gene family 6; transmembrane channel-like protein 6
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11322
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.20 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q7Z403
Gene Symbols
TMC6
Immunogen
Recombinant Protein corresonding to Human TMC6
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: YYNRTVQLRC RSSRPLLGNF VRSAWPSLRL YDLELDPTAL EEEEKQSLLV KELQSLAVAQ RDHMLRGMPL SLAEKRSLRE KSRT TMC6 interacts with, and forms a complex with the zinc transporter 1, SLC30A1, and localizes to the endoplasmic reticulum, nuclear membrane and Golgi apparatus
- The inactivation of the TMC6 gene has been implicated in the skin disorder epidermodysplasia verruciformis (EV), an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin
- EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3
- TMC6 encodes integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels
- This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs
- Diseases associated with TMC6 include Epidermodysplasia Verruciformis and Superficial Mycosis.