PIPA5111494

NR4A1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5111494-Each-of-1 In Stock ₹ 48,905.50

PIPA5111494 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

NR4A1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NR4A1

Gene Alias

early response protein NAK1; Gfrp; GFRP1; growth factor-inducible nuclear protein N10; Hbr1; Hbr-1; Hmr; hormone receptor; immediate early gene transcription factor NGFI-B; MGC9485; N10; NAK1; NAK-1; nerve growth factor IB nuclear receptor variant 1; nerve growth factor induced protein I-B; nerve growth factor-induced protein I-B; Ngfib; NGFI-B; NP10; Nr4a1; Nuclear hormone receptor NUR/77; nuclear protein N10; Nuclear receptor subfamily 4 group A member 1; nuclear receptor subfamily 4, group A, member 1; NUR77; Orphan nuclear receptor HMR; orphan nuclear receptor TR3; Orphan receptor tr3; ST-59; steroid receptor TR3; testicular receptor 3; TIS1; TR3; TR3 orphan receptor

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3164

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.10 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P22736

Gene Symbols

NR4A1

Immunogen

Recombinant Protein corresonding to Human NR4A1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PASASFKFED FQVYGCYPGP LSGPVDEALS SSGSDYYGSP CSAPSPSTPS FQPPQLSPWD GSFGHFSPSQ TYEGLRAWTE QLPKASG NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily
  • NGFI-B-alpha is expressed in brain, adrenal, thyroid, liver, testis, ovary, thymus, muscle, lung and prostate
  • Its expression is induced in response to various stress stimuli and growth factors
  • The encoded protein acts as a nuclear transcription factor involved in mediating apoptotic signaling in thymocytes and tumor cells, as well as having a role in signaling in the hypothalamic-pituitary axis
  • Translocation of the protein from the nucleus to mitochondria induces apoptosis
  • Three transcript variants encoding two distinct isoforms have been identified for this NR4A1
  • Variant (3), also known as TRC beta, contains multiple differences compared to variant 1
  • The resulting isoform b contains a shorter and distinct C-terminus compared to isoform a
  • RXR has been shown to be a partner for NR4A1.