PIPA5111603

ROR gamma Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5111603-Each-of-1 In Stock ₹ 48,905.50

PIPA5111603 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

ROR gamma

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RORC

Gene Alias

IMD42; Nr1f3; Nuclear receptor ROR-gamma; nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; RAR related orphan receptor C; RAR-related orphan nuclear receptor variant 2; RAR-related orphan receptor C; RAR-related orphan receptor C, isoform a; RAR-related orphan receptor gamma; retinoic acid-binding receptor gamma; retinoid-related orphan receptor gamma; retinoid-related orphan receptor-gamma; RORC; RORG; RORgamma; RZRG; RZR-GAMMA; Thor; Thymus orphan receptor; TOR

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6097

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.10 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P51449

Gene Symbols

RORC

Immunogen

Recombinant Protein corresonding to Human ROR gamma

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: FRSTPEAPYA SLTEIEHLVQ SVCKSYRETC QLRLEDLLRQ RSNIFSREEV TGYQRKSMWE MWERCAHHLT EAIQYV ROR gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily
  • Reports suggest thatROR gammais a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis
  • ROR gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells
  • ROR gamma shares 50 to 51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma
  • It is highly expressed in skeletal muscle and at lower levels in various other tissues.