IGFBP5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5111496-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA5111496 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
IGFBP5
Classification
Polyclonal
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P24593
Gene Symbols
IGFBP5
Immunogen
Recombinant Protein corresonding to Human IGFBP5
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry
Conjugate
Unconjugated
Gene
IGFBP5
Gene Alias
AI256729; AW208790; IBP 5; IBP5; IBP-5; IGF BP5; IGF-binding protein 5; IGFBP; IGFBP 5; Igfbp5; IGF-BP5; Igfbp-5; IGFBP-5P; Insulin like growth factor binding protein; insulin like growth factor binding protein 5; insulin-like growth factor binding protein 5; insulin-like growth factor binding protein-5; insulin-like growth factor-binding protein 5
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3488
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Immunogen sequence: DRRKKLTQSK FVGGAENTAH PRIISAPEMR QESEQGPCRR HMEASLQELK ASPRMV The insulin-like growth factor-binding proteins, or IGFBPs, are a family of homologous proteins that have co-evolved with the IGFs
- They serve not only as shuttle molecules for the soluble IGFs, but also confer a level of regulation to the IGF signaling system
- Physical association of the IGFBPs with IGF influences the bio-availability of the growth factors, as well as their concentration and distribution in the extracellular environment
- In addition, the IGFBPs appear to have biological activity independent of the IGFs
- Seven IGFBPs have thus far been described, each differing in their tissue distribution, half-lives and modulation of IGF interactions with their receptors
- For instance, IGFBP1 is negatively regulated by insulin production
- The IGFBP1 gene is expressed at a high level during fetal liver development and in response to nutritional changes and diabetes
- It has been suggested that IGFBP2 functions as chaperone, escorting IGFs to their target tissues
- It is expressed in several human tissues including fetal eye and fetal brain
- IGFBP3 is the most abundant IGFBP and is complexed with roughly 80% of the serum IGFs
- Both IGFBP3 and IGFBP4 are released by dermal fibroblasts in response to incision injury
- IGFBP5 is secreted by myoblasts and may play a key role in muscle differentiation.