PIPA5112055

Langerin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112055-Each-of-1 In Stock ₹ 43,120.50

PIPA5112055 - Each of 1

₹ 43,120.50

In Stock

Quantity

1

Base Price: ₹ 43,120.50

GST (18%): ₹ 7,761.69

Total Price: ₹ 50,882.19

Antigen

Langerin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD207

Gene Alias

CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

50489

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q9UJ71

Gene Symbols

CD207

Immunogen

A synthetic peptide corresponding to the N-terminus of the human cd207

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells
  • Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD)
  • Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules
  • Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG)
  • Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.