PIPA5112357

Placental Alkaline Phosphatase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112357-Each-of-1 In Stock ₹ 42,497.50

PIPA5112357 - Each of 1

₹ 42,497.50

In Stock

Quantity

1

Base Price: ₹ 42,497.50

GST (18%): ₹ 7,649.55

Total Price: ₹ 50,147.05

Antigen

Placental Alkaline Phosphatase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ALPP

Gene Alias

Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; alkaline phosphatase, placental; alkaline phosphatase, placental type; alkaline phosphomonoesterase; ALP; Alp1; ALPP; AP-TNAP; DOA1; FLJ11281; FLJ40094; FLJ61142; FLJ93059; Germ-cell alkaline phosphatase; glycerophosphatase; HOPS; MGC161443; MGC167935; nagao Isozyme; P PLAP; PALP; PLA2P; PLAA; placental alkaline phosphatase 1; placental heat-stable alkaline phosphatase; PLAP; PLAP1; PLAP-1; rCG23846-like; Regan isozyme; TNAP; TNSALP

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

250

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.88 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P05187

Gene Symbols

ALPP

Immunogen

Recombinant Human Alkaline phosphatase, placental type protein (260-520AA)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Placental Alkaline Phosphatase plays an important role in the regulation of specific inflammatory disease processes
  • There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney for this form of alkaline phosphatase have been well characterized
  • Placental Alkaline Phosphatase reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation
  • Placental Alkaline Phosphatase is useful in the identification of testicular germ cell tumors
  • Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA)
  • A proposed function of Placental Alkaline Phosphatase is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development
  • Placental Alkaline Phosphatase has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects
  • The character of hypophosphatasia can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.