PIPA5112433

GSTM3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5112433-Each-of-1 In Stock ₹ 42,497.50

PIPA5112433 - Each of 1

₹ 42,497.50

In Stock

Quantity

1

Base Price: ₹ 42,497.50

GST (18%): ₹ 7,649.55

Total Price: ₹ 50,147.05

Antigen

GSTM3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GSTM3

Gene Alias

brain GST; brain type mu-glutathione S-transferase; Fsc2; glutathione S-alkyltransferase M3; glutathione S-aralkyltransferase M3; glutathione S-aryltransferase M3; glutathione S-transferase GT9.3; glutathione S-transferase M3 (brain); glutathione S-transferase Mu 3; glutathione S-transferase mu 3 (brain); glutathione S-transferase, mu 3; glutathione S-transferase, Mu-3; GST class-mu 3; GST5; GSTB; GSTM3; GSTM3-3; GTM3; hGSTM3-3; mGSTM5; S-(hydroxyalkyl)glutathione lyase M3

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

14864, 2947

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

3.5 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

P19639, P21266

Gene Symbols

GSTM3

Immunogen

Recombinant Human Glutathione S-transferase Mu 3 protein (1-225AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Glutathione S-transferase M3 (brain), also known as GSTM3, is an enzyme which in humans is encoded by theGSTM3 gene
  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families
  • At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta
  • This gene encodes a glutathione S-transferase that belongs to the mu class
  • The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione
  • The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13
  • 3 and are known to be highly polymorphic
  • These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs
  • Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins.