TPPP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5112775-Each-of-1 | In Stock | ₹ 42,497.50 |
PIPA5112775 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,497.50
GST (18%): ₹ 7,649.55
Total Price: ₹ 50,147.05
Antigen
TPPP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TPPP
Gene Alias
25 kDa brain-specific protein; 2900041A09Rik; AI849835; brain specific protein p25 alpha; brain-specific protein p25 alpha; glycogen synthase kinase 3 (GSK3) inhibitor p24; p24; p25; p25alpha; p25-alpha; RGD1310121; Tppp; TPPP/p25; TPPP1; tubulin polymerization promoting protein; tubulin polymerization-promoting protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11076, 72948
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.28 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O94811, Q7TQD2
Gene Symbols
TPPP
Immunogen
Recombinant Human Tubulin polymerization-promoting protein (1-219AA)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Tubulin family members are globular proteins important in the assembly of microtubules
- Microtubules are structural components that play important roles in mitosis, cytokinesis and vesicle transport
- TPPP (Tubulin polymerization-promoting protein), also known as p24 and p25, is a widely expressed 219 amino acid protein found in the perinuclear region of the cytoplasm
- TPPP may form dimers and functions in polymerizing tubulin into double-walled tubules, polymorphic aggregates, or stabilized blocks
- TPPP overexpression prevents formation of the mitotic spindle assembly and breakdown of the nuclear envelope
- TPPP is phosphorylated by TPK II and is encoded by a gene that maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome
- May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network
- May play a role in mitotic spindle assembly and nuclear envelope breakdown.