PIPA5113518

FBXL21 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5113518-Each-of-1 In Stock ₹ 43,120.50

PIPA5113518 - Each of 1

₹ 43,120.50

In Stock

Quantity

1

Base Price: ₹ 43,120.50

GST (18%): ₹ 7,761.69

Total Price: ₹ 50,882.19

Antigen

FBXL21

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FBXL21

Gene Alias

D630045D17Rik; Fbl21; FBL3B; F-box and leucine rich repeat protein 21 (gene/pseudogene); F-box and leucine-rich repeat protein 21; F-box and leucine-rich repeat protein 3 pseudogene; F-box and leucine-rich repeat protein 3, pseudogene 1; F-box and leucine-rich repeat protein 3B; F-box protein Fbl3b; F-box/LRR-repeat protein 21; F-box/LRR-repeat protein 3B; Fbxl21; Fbxl3b; Fbxl3p; Fbxl3-ps1; Psttm

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

213311, 26223

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

5 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

Q8BFZ4, Q9UKT6

Gene Symbols

FBXL21

Immunogen

Recombinant Human F-box/LRR-repeat protein 21 protein (78-137AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • FBL3B is a 434 amino acid protein encoded by the human gene FBXL21
  • FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family
  • FBL3B also contains three LRR (leucine-rich) repeats
  • F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination
  • F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination
  • FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1
  • FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.