PIPA5114452

Emerin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114452-Each-of-1 In Stock ₹ 46,502.50

PIPA5114452 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Emerin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Emd

Gene Alias

AW550900; EDMD; EMD; Emerin; LEM domain containing 5; LEMD5; STA

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13726, 2010, 25437

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O08579, P50402, Q63190

Gene Symbols

Emd

Immunogen

Emerin antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human Emerin. The immunogen is located within the first 50 amino acids of Emerin.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive controls that may be used include: Human Skeletal Muscle Tissue Lysate Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight
  • The XPG protein, a member of the flap endonuclease 1 (FEN-1) structure-specific DNA repair endonuclease family, is an enzyme essential for DNA repair of the major kinds of solar μgtraviolet (UV)-induced DNA damages
  • Human XPG nuclease makes the 3' incision during nucleotide excision repair of DNA
  • The enzyme cleaves model DNA bubble structures specifically near the junction of unpaired DNA with a duplex region
  • A 29-amino acid region of human XPG (residues 981-1009) contains the PCNA binding activity
  • A conserved arginine in XPG (Arg992) is crucial for its PCNA binding activity
  • Replication Protein A (RPA) binds specifically and directly to two excision repair proteins, the xeroderma pigmentosum damage-recognition protein XPA and the endonuclease XPG.