PIPA5114490

E2F3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114490-Each-of-1 In Stock ₹ 46,502.50

PIPA5114490 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

E2F3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

E2F3

Gene Alias

DKFZp686C18211; E2F transcription factor 3; E2f3; E2F-3; E2f3a; E2F3b; KIAA0075; MGC104598; RGD1561600; RP1-177P22.2; Transcription factor E2F3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13557, 1871

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O00716, O35261

Gene Symbols

E2F3

Immunogen

E2F3 antibody was raised against a 15 amino acid peptide near the center of human E2F3. The immunogen is located within amino acids 150 - 200 of E2F3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive controls that may be used include: Human Lymph node Tissue Lysate, Human Lymphoid Tissue Slide The protein encoded by this gene is a member of the E2F family of transcription factors
  • The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses
  • The E2F proteins contain several evolutionally conserved domains found in most members of the family
  • These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain
  • This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain
  • This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.