KIR2DS2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114507-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5114507 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
KIR2DS2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KIR2DS2
Gene Alias
1060P11.9.2; 183ActI; CD158 antigen-like family member J; CD158b; CD158J; cl-49; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2; killer cell immunoglobulin-like receptor 2DS2; killer cell immunoglobulin-like receptor KIR2DS2; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2; killer-cell Ig-like receptor; killer-cell immunoglobulin-like receptor two domains short tail 2 protein; KIR2DS2; KIR-2DS2; MHC class I NK cell receptor; na; natural killer associated transcript 5; natural killer cell inhibitory receptor; natural killer cell receptor; Natural killer-associated transcript 5; NK receptor 183 ActI; NKAT5; NKAT-5; p58 killer cell inhibitory receptor KIR-K7a; p58 natural killer cell receptor clone CL-49; p58 NK receptor CL-49
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100132285
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P43631
Gene Symbols
KIR2DS2
Immunogen
KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. The immunogen is located within the last 50 amino acids of KIR2DS2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive controls that may be used include: HEK293 Cell Lysate, HEK293 Cell Slide Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells
- The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC)
- The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2)
- The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain
- KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals
- The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.