LILRB2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116507-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5116507 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
LILRB2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LILRB2
Gene Alias
CD85 antigen-like family member D; CD85D; CD85d antigen; Ig-like transcript 4; ILT4; ILT-4; leucocyte Ig-like receptor B2; leukocyte immunoglobulin like receptor B2; leukocyte immunoglobulin-like receptor subfamily B member 2; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; LILRB2; Lilrb3; LIR2; LIR-2; LIR2CD85D; MIR10; MIR-10; MIR10LILRA6; monocyte/macrophage immunoglobulin-like receptor 10; myeloid inhibitory receptor 10; Neutrophil immunoglobulin-like receptor 1; Nilr1; NILR-1; paired-Ig-like receptor B; Pirb; type 1 one-pass transmembrane Ig-like receptor
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-240 of human LILRB2/CD85d/ILT4 (NP_0058653)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Concentration
1.39 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q8N423
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10288, 65146
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- Positive Samples: Mouse liver, Mouse kidney, Mouse blood cell, Rat liver, Rat kidney, Rat blood cell Immunogen sequence: QTGTIPKPTL WAEPDSVITQ GSPVTLSCQG SLEAQEYRLY REKKSASWIT RIRPELVKNG QFHIPSITWE HTGRYGCQYY SRARWSELSD PLVLVMTGAY PKPTLSAQPS PVVTSGGRVT LQCESQVAFG GFILCKEGED EHPQCLNSQP HARGSSRAIF SVGPVSPNRR WSHRCYGYDL NSPYVWSSPS DLLELLVPGV SKKPSLSVQP GPVMAPGES LILRB2 (ILT4) gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4
- The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs)
- The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response
- It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity
- Multiple transcript variants encoding different isoforms have been found for this gene.