Phospho-JIP1 (Thr205) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114595-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5114595 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-JIP1 (Thr205)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAPK8IP1
Gene Alias
C-Jun-amino-terminal kinase-interacting protein 1; Ib1; IB-1; Islet-brain 1; islet-brain-1; JIP1; JIP-1; JIP-1-related protein; JNK MAP kinase scaffold protein 1; JNK-interacting protein 1; JRP; Mapk8ip; Mapk8ip1; mitogen activated protein kinase 8 interacting protein; mitogen activated protein kinase 8 interacting protein 1; mitogen-activated protein kinase 8 interacting protein 1; mitogen-activated protein kinase 8-interacting protein 1; mjip-2a; PRKM8 interacting protein; PRKM8IP; protein kinase, mitogen-activated 8 interacting protein; Skip
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116457, 19099, 9479
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q9R237, Q9UQF2, Q9WVI9
Gene Symbols
MAPK8IP1
Immunogen
A synthesized peptide derived from human JIP1 around the phosphorylation site of Thr205.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of JIP1 only when phosphorylated at Thr205
- The protein encoded by this gene is a regulator of the pancreatic beta-cell function
- It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8)
- This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells
- This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2
- RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells
- This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.