PIPA5114711

Cyclin T1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114711-Each-of-1 In Stock ₹ 46,502.50

PIPA5114711 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Cyclin T1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ccnt1

Gene Alias

2810478G24Rik; AI115585; CCNT; CCNT1; CDK9-associated C-type protein; cyclin C-related protein; cyclin T1; cyclin T1b; cyclin-T; cyclin-T1; CycT1; HIVE1; human immunodeficiency virus type 1 (HIV-1) expression (elevated) 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12455, 904

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (PFA fixed), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

O60563, Q9QWV9

Gene Symbols

Ccnt1

Immunogen

A synthesized peptide derived from human CCNT1(Accession O60563), corresponding to amino acid residues P678-K726.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total CCNT1
  • This gene encodes a member of the highly conserved cyclin C subfamily
  • The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb)
  • In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9
  • The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription
  • This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit
  • Overexpression of this gene is implicated in tumor growth
  • Alternative splicing results in multiple transcript variants.