PIPA511480

AFP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA511480-Each-of-1 In Stock ₹ 46,502.50

PIPA511480 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

AFP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AFP

Gene Alias

a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

174

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.3 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P02771

Gene Symbols

AFP

Immunogen

KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human AFP

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life
  • AFP expression in adults is often associated with hepatoma or teratoma
  • However, hereditary persistence of AFP may also be found in individuals with no obvious pathology
  • The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4
  • AFP is found in monomeric, dimeric, and trimeric forms
  • AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin
  • The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly
  • High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.