SNAP alpha Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117112-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117112 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SNAP alpha
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NAPA
Gene Alias
1500039N14Rik; alpha snap; alpha soluble NSF attachment protein; alpha-SNAP; Alpha-soluble NSF attachment protein; a-SNAP; AW209189; hydrocephaly with hop gait; hyh; Napa; N-ethylmaleimide sensitive fusion protein attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein, alpha; NSF attachment protein alpha; RA81; Snap; SNAPA; SNAP-alpha; SNARE
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
108124, 140673, 8775
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.6 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P54920, P54921, Q9DB05
Gene Symbols
NAPA
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human Alpha SNAP (NP_0038182)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: HL-60, THP-1, HeLa, Jurkat, Mouse brain, Mouse lung, Mouse heart, Mouse pancreas, Rat liver Immunogen sequence: MDNSGKEAEA MALLAEAERK VKNSQSFFSG LFGGSSKIEE ACEIYARAAN MFKMAKNWSA AGNAFCQAAQ LHLQLQSKHD AATCFVDAGN AFKKADPQEA INCLMRAIEI YTDMGRFTIA AKHHISIAEI YETELVDIEK AIAHYEQSAD YYKGEESNSS ANKCLLKVAG YAALLEQYQK AIDIYEQVGT NAMDSPLLKY SAKDYFFKAA LCHFCIDMLN AKLAVQKYEE LFPAFSDSRE CKLMKKLLEA HEEQNVDSYT ESVKEYDSIS RLDQWLTTML LRIKKTIQGD EEDLR SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion and transcytotic vesicles-to-plasma membrane transport
- Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE
- a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle
- It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.