alpha Actinin 1/2/3/4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114820-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5114820 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
alpha Actinin 1/2/3/4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Actn4
Gene Alias
1110008F24Rik; 3110023F10Rik; actinin 1 smooth muscle; actinin alpha 1; actinin alpha 2; actinin alpha 3; actinin alpha 3 (gene/pseudogene); actinin alpha 4; actinin, alpha 1; actinin, alpha 2; actinin, alpha 3; ACTININ-4; ACTN1; Actn1a; ACTN2; Actn3; Actn4; alpha actinin 1a; alpha actinin 4; alpha-actinin cytoskeletal isoform; alpha-actinin skeletal muscle; Alpha-actinin skeletal muscle isoform 2; Alpha-actinin skeletal muscle isoform 3; Alpha-actinin-1; alpha-actinin-2; Alpha-actinin-3; alpha-actinin-4; BDPLT15; C77391; CMD1AA; CMH23; F-actin cross-linking protein; focal segmental glomerulosclerosis 1; FSGS; FSGS1; non-muscle alpha-actinin 1; non-muscle alpha-actinin 4; Non-muscle alpha-actinin-1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
109711, 11472, 11474, 171009, 291245, 60595, 63836, 81, 81634, 87, 88, 89
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
O43707, O88990, P12814, P35609, P57780, Q08043, Q7TPR4, Q9JI91, Q9QXQ0, Q9Z1P2
Gene Symbols
ACTN1, Actn2, Actn3, Actn4
Immunogen
A synthesized peptide derived from human ACTN1/2/3/4.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total ACTN1/2/3/4
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins
- Alpha actinin is an actin-binding protein with multiple roles in different cell types
- In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane
- In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments
- This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene
- Three transcript variants encoding different isoforms have been found for this gene.