PIPA5114843

Spectrin alpha-1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114843-Each-of-1 In Stock ₹ 46,502.50

PIPA5114843 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Spectrin alpha-1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPTA1

Gene Alias

2610027H02Rik; A2a; AF093576; a--fodrin; AI451697; alpha II spectrin; alpha-fodrin; alpha-I spectrin; alpha-II spectrin; alpha-spectrin 1, erythroid; alpha-spectrin 2; alpha-spectrin 2, brain; brain alpha-spectrin; EIEE5; EL2; elliptocytosis 2; erythroid alpha-spectrin; erythroid spectrin alpha; fodrin alpha chain; ha; hemolytic anemia; HPP; HS3; ihj; inhibitory protein factor; IPF; mutant alpha spectrin; NEAS; neuroscience mutagenesis facility, 4; nmf4; noerythroid alpha-spectrin 2; nonerythroid alpha-spectrin 2; spectrin alpha 1; spectrin alpha chain, brain; spectrin alpha chain, erythrocyte; spectrin alpha chain, erythrocytic 1; Spectrin alpha chain, non-erythrocytic 1; spectrin alpha, erythrocytic 1; spectrin alpha, non-erythrocytic 1; spectrin, alpha, erythrocytic 1; spectrin, alpha, erythrocytic 1 (elliptocytosis 2); spectrin, alpha, non-erythrocytic 1; spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit; sph; SPH3; spherocytosis; Spna1; Spna-1; Spna2; Spna

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20739, 289257, 6708

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P02549, P08032

Gene Symbols

SPTA1

Immunogen

A synthesized peptide derived from human SPTA1(Accession P02549), corresponding to amino acid residues M2376-N2419.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total alpha 1 Spectrin
  • Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles
  • It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement
  • This gene is one member of a family of alpha-spectrin genes
  • The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation
  • It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells
  • Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia
  • [provided by RefSeq, Jul 2008]