PIPA5116357

MTM1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5116357-Each-of-1 In Stock ₹ 46,502.50

PIPA5116357 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MTM1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MTM1

Gene Alias

AF073996; CG2; CNM; fb19c01; hypothetical protein LOC560881; im:6903724; mKIAA4176; Mtm; MTM1; MTMX; myotubularin; myotubularin 1; Myotubularin-like protein; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase; wu:fb19c01; X-linked myotubular myopathy gene 1; XLMTM; zgc:123266

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

560881

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.4 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

0

Gene Symbols

MTM1

Immunogen

KLH conjugated synthetic peptide between 451-485 amino acids from the region of DANRE mtm1

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Zebrafish

Product Type

Antibody

Isotype

IgG

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Description

  • Human MTM1, a 603 amino-acid protein, is mutated in myotubular myopathy
  • The largely related protein hMTMR2 is found mutated in a recessive form of Charcot-Marie-tooth neuropathy
  • Myotubularin is primarily a lipid phosphatase that acts on hosphatidylinositol 3-monophosphate and is involved in the regulation of the phosphatidylinositol 3-kinase (PI 3-kinase) pathway and membrane trafficking
  • Wildtype myotubularin can directly dephosphorylate PI 3-P and PI 4-P in vitro
  • Thus, it decreases PI 3-P levels by down-regulating PI 3-K activity and by facilitating the degradation of PI 3-P.