PIPA5116743

PILRA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5116743-Each-of-1 In Stock ₹ 46,502.50

PIPA5116743 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

PILRA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PILRA

Gene Alias

AV021745; cell surface receptor FDF03; FDF03; Inhibitory receptor PILR-alpha; paired immunoglobin like type 2 receptor alpha; paired immunoglobin-like type 2 receptor alpha; paired immunoglobulin-like type 2 receptor alpha; Pilra

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

231805, 288568

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.74 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

Q2YFS3

Gene Symbols

PILRA

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-180 of human PILRA (NP_8400561)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: Mouse liver, Rat liver Immunogen sequence: QPSGSTGSGP SYLYGVTQPK HLSASMGGSV EIPFSFYYPW ELATAPDVRI SWRRGHFHRQ SFYSTRPPSI HKDYVNRLFL NWTEGQKSGF LRISNLQKQD QSVYFCRVEL DTRSSGRQQW QSIEGTKLSI TQGQQRTKAT TPAREPFQNT EEPYENIRNE G SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways
  • Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts
  • Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILR beta-mediated activation
  • This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes
  • SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways
  • Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts
  • Control of cell signaling via SHP-1 is thought to occur through a balance between PILR alpha-mediated inhibition and PILRbeta-mediated activation
  • These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7
  • This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role.