PIPA5116873

Methyl-YAP1 (Lys342) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5116873-Each-of-1 In Stock ₹ 46,502.50

PIPA5116873 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Methyl-YAP1 (Lys342)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

YAP1

Gene Alias

65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10413, 22601, 363014

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.35 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P46937, P46938, Q2EJA0

Gene Symbols

YAP1

Immunogen

A synthetic monomethylated peptide around K342 of human YAP1 (NP_0011236171)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: Mouse kidney, Rat liver Immunogen sequence: SPKCQ YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene
  • Its gene is transcriptionally activated in squamous cell carcinoma cells
  • YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway
  • The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis
  • Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration
  • Mutations in the IRF5 gene results in coloboma.