mGluR8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA511697-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA511697 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
mGluR8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GRM8
Gene Alias
A230002O04; FLJ41058; G protein coupled receptor, family C, group 1, member H; G protein-coupled receptor family C group 1 member H; G protein-coupled receptor, family C, group 1, member H; GLUR8; glutamate metabotropic receptor 8; glutamate receptor; glutamate receptor, metabotropic 8; Gprc1h; Grm8; M mGlu8; Metabotropic glutamate receptor 8; metabotropic glutamate receptor subtype 8b; MGC126724; mGlu8; mGlur; mGluR8; mGluR8b
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
14823, 2918
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.7 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
O00222, P47743
Gene Symbols
GRM8
Immunogen
KLH conjugated synthetic peptide between 852-882 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 8
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with rat based on sequence homology
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors
- Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions
- The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties
- Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C
- Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8
- Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.