PIPA5117012
Amphiphysin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117012-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117012 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Amphiphysin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Amph
Gene Alias
Amph; AMPH1; amphiphysin; amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen); amphiphysin 1; amphiphysin I; HGNC:471
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
218038, 273, 60668
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1.23 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
O08838, P49418, Q7TQF7
Gene Symbols
Amph
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human AMPH (NP_0016261)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: Mouse brain, Rat brain Immunogen sequence: MADIKTGIFA KNVQKRLNRA QEKVLQKLGK ADETKDEQFE EYVQNFKRQE AEGTRLQREL RGYLAAIKGM QEASMKLTES LHEVYEPDWY GREDVKMVGE KCDVLWEDFH QKLVDGSLLT LDTYLGQFPD IKNRIAKRSR KLVDYDSARH HLEALQSSKR KDESRISKAE EEFQKAQKVF EEFNVDLQEE LPSLWSRRVG FYVNTFKNVS SLEAKFHKEI AVLCHKLYEV MTKLGDQHAD KAFTIQGAPS Amphiphysins, members of the BAR (Bin-Amphiphysin-Rvsp) protein super family, play a key role in clathrin-mediated endocytosis of synaptic vesicles (SVs)
- All members of the BAR family share a highly conserved N-terminal BAR domain and a C-terminal Src homology (SH3) domain
- Two isoforms of amphiphysin have been identified and act in concert as a heterodimer
- Amphiphysins interact via its carboxy-terminal SH3 domain with dynamin, synaptojanin and clathrin
- These complexes are implicated in synaptic vesicle recycling at nerve terminal
- Amphiphysins were also identified as the dominant autoantigen in paraneoplastic Stiff-Man Syndrome.