WDR48 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117073-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117073 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
WDR48
Classification
Polyclonal
Conjugate
Unconjugated
Gene
WDR48
Gene Alias
8430408H12Rik; KIAA1449; mKIAA1449; P80; RGD1309702; SPG60; testicular tissue protein Li 224; Uaf1; USP1 associated factor 1; USP1-associated factor 1; WD repeat domain 48; WD repeat endosomal protein; WD repeat-containing protein 48; WDR48
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
363164, 57599, 67561
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.7 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q8BH57, Q8TAF3
Gene Symbols
WDR48
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 450-677 of human WDR48 (NP_0658901)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: U-251MG, A-431, SGC-7901, LO2, A-549, HT-1080, Mouse brain, Rat testis Immunogen sequence: FSSPDGSDPK LNLGGLLLQA LLEYWPRTHV NPMDEEENEV NHVNGEQENR VQKGNGYFQV PPHTPVIFGE AGGRTLFRLL CRDSGGETES MLLNETVPQW VIDITVDKNM PKFNKIPFYL QPHASSGAKT LKKDRLSASD MLQVRKVMEH VYEKIINLDN ESQTTSSSNN EKPGEQEKEE DIAVLAEEKI ELLCQDQVLD PNMDLRTVKH FIWKSGGDLT LHYRQKST WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids, which commonly form a tertiary propeller structure
- While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms involving signal transduction, apoptosis, transcriptional regulation and cell cycle control
- WD repeats serve as sites for protein-protein interaction and some seem to mediate the assembly of protein complexes
- With eight WD repeats, WDR48 (WD repeat-containing protein 48), also known as USP1-associated factor 1 and p80, is a 677 amino acid protein that functions to regulate deubiquitinating complexes via activation of USP1, USP12 and USP46
- WDR48 enhances deubiquitination by increasing catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate
- WDR48 is ubiquitously expressed and is mainly localized to the cytoplasm
- There are five isoforms of WDR48 that are expressed as a result of alternative splicing events.