PC4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117086-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117086 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PC4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Sub1
Gene Alias
activated RNA polymerase II transcription cofactor 4; activated RNA polymerase II transcriptional coactivator p15; AI842364; hypothetical protein LOC553561; p14; P15; P9; Pc4; positive cofactor 4; pR-ET2 encoded oncodevelopmental protein; RNA polymerase II transcriptional coactivator; Rpo2tc1; Single-stranded DNA-binding protein p9; Sub1; SUB1 homolog; SUB1 homolog (S. cerevisiae); SUB1 homolog a; SUB1 homolog, transcriptional regulator; SUB1 homolog, transcriptional regulator a; SUB1 regulator of transcription; SUB1 regulator of transcription a; sub1a; TIS7; zgc:109973
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10923, 20024
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration
0.54 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P11031, P53999
Gene Symbols
Sub1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human SUB1 (NP_0067043)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: HL-60, BT-474, SW620, Jurkat, Mouse brain Immunogen sequence: MPKSKELVSS SSSGSDSDSE VDKKLKRKKQ VAPEKPVKKQ KTGETSRALS SSKQSSSSRD DNMFQIGKMR YVSVRDFKGK VLIDIREYWM DPEGEMKPGR KGISLNPEQW SQLKEQISDI DDAVRKL PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity
- The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH
- TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.