AMPD1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117108-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117108 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
AMPD1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AMPD1
Gene Alias
adenosine monophosphate deaminase 1; adenosine monophosphate deaminase 1 (isoform M); adenosine monophosphate deaminase-1 (muscle); AI553520; AMP deaminase 1; AMP deaminase isoform M; Ampd; Ampd01; AMPD1; Ampd-1; MAD; MADA; MMDD; myoadenylate deaminase; RATAMPD01; RP5-1000E10.1; skeletal muscle AMPD
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
229665, 25028, 270
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P10759, P23109, Q3V1D3
Gene Symbols
AMPD1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human AMPD1 (P23109)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: HT-29, Mouse skeletal muscle, Mouse thymus, Mouse pancreas Immunogen sequence: MNVRIFYSVS QSPHSLLSLL FYCAILESRI SATMPLFKLP AEEKQIDDAM RNFAEKVFAS EVKDEGGRQE ISPFDVDEIC PISHHEMQAH IFHLETLSTS AMP deaminase (AMPD) is an allosteric enzyme involved in the regulation of adenosine metabolism
- It catalyzes a central reaction in purine nucleotide biosynthesis where AMP is deaminated to IMP, liberating ammonia
- There are three functional isoforms of AMPD
- AMPD1 (E.C
- No 3.5.4.6.) is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries
- This protein is the predominant member of AMPD multi-gene family and is considered as the sensor of the cell’s changing energy requirements
- AMPD1 deficiency causes irregular muscle metabolism due to lower rate of ATP degradation, phosphocreatine hydrolysis and accumulation of lactic acid
- Mutated AMPD1 expression has been detected in neuromuscular disorders, exercise-induced skeletal muscle myopathies and congestive heart failures due to coronary artery diseases.