POMGNT1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117164-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117164 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
POMGNT1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
POMGNT1
Gene Alias
0610016I07Rik; 4930467B06Rik; GnT I.2; GNTI.2; gnT-I.2; LGMD2O; MDDGA3; MDDGB3; MDDGC3; MEB; MGAT1.2; N-acetylglucosaminyltransferase I.2; O-linked mannose beta1,2-N-acetylglucosaminyltransferase; O-mannosyl N-acetylglucosaminyltransferase; OMGnT1; POMGNT1; protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase; protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase; protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-); protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1; protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1; LOW QUALITY PROTEIN: protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1; RP11-322N21.3; UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2; UNQ746/PRO1475
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
362567, 55624, 68273
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.49 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q5XIN7, Q8WZA1, Q91X88
Gene Symbols
POMGNT1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 411-660 of human POMGNT1 (NP_0602093)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: SH-SY5Y, Mouse kidney, Mouse heart, Mouse brain, Rat testis Immunogen sequence: HLLEEDDSLY CISAWNDQGY EHTAEDPALL YRVETMPGLG WVLRRSLYKE ELEPKWPTPE KLWDWDMWMR MPEQRRGREC IIPDVSRSYH FGIVGLNMNG YFHEAYFKKH KFNTVPGVQL RNVDSLKKEA YEVEVHRLLS EAEVLDHSKN PCEDSFLPDT EGHTYVAFIR MEKDDDFTTW TQLAKCLHIW DLDVRGNHRG LWRLFRKKNH FLVVGVPASP YSVKKPPSVT PIFLEPPPKE EGAPGAPEQT The product of the POMGNT1 gene, protein O-mannose beta-1,2-N-acetylglucosaminyltransferase, participates in O-mannosyl glycan synthesis
- POMGnT1 is an N(in)/C(out) (type II) membrane protein localized in the medial-Golgi that initiates the conversion of high mannose N-glycans to complex N-glycans
- Specifically, POMGnT1 is a glycosylation enzyme that participates in the synthesis of O-mannosyl glycan, a laminin-binding ligand of alpha-dystroglycan that is rarely synthesized in mammals
- Mutations in the POMGNT1 gene cause muscle-eye-brain disease (MEB), an autosomal recessive disorder characterized by congenital muscular dystrophy, ocular abnormalities and lissencephaly.