PIPA5117269

Phospho-AMPK beta-1 (Ser182) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5117269-Each-of-1 In Stock ₹ 47,392.50

PIPA5117269 - Each of 1

₹ 47,392.50

In Stock

Quantity

1

Base Price: ₹ 47,392.50

GST (18%): ₹ 8,530.65

Total Price: ₹ 55,923.15

Antigen

Phospho-AMPK beta-1 (Ser182)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRKAB1

Gene Alias

1300015D22Rik; 5'-AMP-activated protein kinase 40 kDa subunit; 5-AMP-activated protein kinase beta subunit; 5'-AMP-activated protein kinase beta-1 subunit; 5'-AMP-activated protein kinase subunit beta-1; 5'-AMP-activated protein kinase subunit beta-1-like protein; 5'-AMP-activated protein kinase, beta subunit; AAKB1; AMP-activated protein kinase beta subunit; AMPK; AMPK beta 1; AMPK beta -1 chain; AMPK beta-1 chain; AMPK subunit beta-1; AMPKb; AMPK-beta1; AU021155; E430008F22; HAMPKb; kinase AMPK-beta1; kinase pAMPK; pAMPK; Prkab1; protein kinase AMP-activated non-catalytic subunit beta 1; protein kinase, AMP-activated, beta 1 non-catalytic subunit; protein kinase, AMP-activated, noncatalytic, beta-1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19079, 5564, 83803

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

2.91 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P80386, Q9R078, Q9Y478

Gene Symbols

PRKAB1

Immunogen

A synthetic phosphorylated peptide around S182 of human AMPKbeta1 (NP_0062442)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: C2C12 Immunogen sequence: SSSPP AMPK beta 1 is a regulatory subunit of the AMP-activated protein kinase (AMPK)
  • AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits
  • AMPK is an important energy-sensing enzyme that monitors cellular energy status
  • In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol
  • This subunit may be a positive regulator of AMPK activity
  • The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK
  • This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.