MLK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5117296-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5117296 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
MLK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAP3K9
Gene Alias
E130314H24Rik; Map3k9; MEKK9; mitogen activated protein kinase kinase kinase 9; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); mixed-lineage kinase 1; MLK1; Prke1; RGD1562149
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4293
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P80192
Gene Symbols
MAP3K9
Immunogen
Recombinant protein encompassing a sequence within the center region of human MLK1. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
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Description
- Centrifuge briefly prior to opening
- MAP3K9 (MLK1) is a serine/threonine protein kinase that functions in the MAP kinase pathway
- Plays an important role in the cascades of cellular responses evoked by changes in the environment
- Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs
- The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors
- Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.