PIPA5117361

TRF2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5117361-Each-of-1 In Stock ₹ 46,502.50

PIPA5117361 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TRF2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TERF2

Gene Alias

Telomeric DNA-binding protein; telomeric repeat binding factor 2; telomeric repeat binding protein 2; telomeric repeat-binding factor 2; TERF2; TRBF2; TRF2; TTAGGG repeat-binding factor 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7014

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.47 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

Q15554

Gene Symbols

TERF2

Immunogen

Recombinant protein encompassing a sequence within the center region of human TRF2. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Centrifuge briefly prior to opening
  • TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length
  • TRF2, like TRF1 contains a Myb-related DNA binding motif
  • It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes
  • TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini
  • The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells
  • Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types.