PIPA5117445

PERP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5117445-Each-of-1 In Stock ₹ 45,434.50

PIPA5117445 - Each of 1

₹ 45,434.50

In Stock

Quantity

1

Base Price: ₹ 45,434.50

GST (18%): ₹ 8,178.21

Total Price: ₹ 53,612.71

Antigen

PERP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PERP

Gene Alias

1110017A08Rik; dJ496H19.1; HGNC:17637; KCP1; KCP-1; keratinocyte associated protein 1; keratinocyte-associated protein 1; keratinocytes associated protein 1; KRTCAP1; p53 apoptosis effector related to PMP22; p53 apoptosis effector related to PMP-22; p53 apoptosis-associated target; p53-induced protein PIGPC1; PERP; PERP, TP53 apoptosis effector; PIGPC1; RP3-496H19.1; THW; Transmembrane protein THW

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

64065

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.58 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

Q96FX8

Gene Symbols

PERP

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PERP. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Centrifuge briefly prior to opening
  • The p53 tumor-suppressor gene integrates numerous signals that control cell life and death
  • Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently
  • PERP, also termed PIGPC1 and THW, is a plasma membrane protein
  • p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis
  • The expression of PERP causes cell death
  • PERP is a mediator of p53 induced apoptosis
  • PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.