PIPA5119752

PDCD6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5119752-Each-of-1 In Stock ₹ 44,811.50

PIPA5119752 - Each of 1

₹ 44,811.50

In Stock

Quantity

1

Base Price: ₹ 44,811.50

GST (18%): ₹ 8,066.07

Total Price: ₹ 52,877.57

Antigen

PDCD6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pdcd6

Gene Alias

Alg2; alg-2; ALG-257; Apoptosis-linked gene 2 protein; Apoptosis-linked gene 2 protein homolog; AV299538; MA-3; PDCD6; PEF1B; PMP41; probable calcium-binding protein ALG-2; programmed cell death 6; programmed cell death protein 6; PS2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10016, 308061

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

G3V7W1, O75340

Gene Symbols

Pdcd6

Immunogen

Recombinant protein within human PDCD6 aa 1-191

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: SK-Br-3 cell lysate, HepG2 cell lysate, rat ovary tissue lysate, human breast carcinoma tissue, human placenta tissue, human stomach carcinoma tissue
  • Subcellular Location: Endosome, Endoplasmic reticulum membrane, Nucleus, COPII-coated vesicle membrane, Cytoplasm
  • An increased intracellular Ca2+ concentration induces apoptotic cell death
  • Transiently elevated Ca2+ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis
  • ALG-2 (for apoptosis-linked gene 2) is a Ca2+ -binding protein that participates in regulatory events occuring late in the apoptotic program and where several death signals converge
  • ALG-2 is a protein expressed in normal brain, and to a greater extent in ischemic brain
  • The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, which includes Calpain small subunits sorcin and Grancalcin.