4EBP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120165-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5120165 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
4EBP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EIF4EBP1
Gene Alias
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116636, 13685, 1978
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.14 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.
Q13541, Q60876, Q62622
Gene Symbols
EIF4EBP1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-118 of human eIF4EBP1 (NP_0040861)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: MCF7, HeLa, SH-SY5Y, NIH/3T3
- Immunogen sequence: TRIIYDRKFL MECRNSPVTK TPPRDLPTIP GVTSPSSDEP PMEASQSHLR NSPEDKRAGG EESQFEMDI This gene encodes one member of a family of translation repressor proteins
- The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs
- Interaction of this protein with eIF4E inhibits complex assembly and represses translation
- This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.