PIPA5120481
AMOTL2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120481-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5120481 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
AMOTL2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AMOTL2
Gene Alias
AMOTL2; angiomotin like 2; angiomotin-like 2; angiomotin-like protein 2; AW549739; C79691; KIAA0989; LCCP; Leman coiled-coil protein; MASCOT; mKIAA0989
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
51421, 56332
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.6 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.
Q8K371, Q9Y2J4
Gene Symbols
AMOTL2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 638-837 of human AMOTL2 (NP_001265612.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: 293T, U-251MG, HepG2, Mouse liver, Mouse brain
- Immunogen sequence: RQFAMDAAAT AAAQRDTTLI RHSPQPSPSS SFNEGLLTGG HRHQEMESRL KVLHAQILEK DAVIKVLQQR SRRDPGKAIQ GSLRPAKSVP SVFAAAAAGT QGWQGLSSSE RQTADAPARL TTDRAPTEEP VVTAPPAAHA KHGSRDGSTQ TEGPPDSTST CLPPEPDSLL GCSSSQRAAS LDSVATSRVQ DLSDMVEILI Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites
- Required for proper architecture of actin filaments
- Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus
- Participates in angiogenesis
- May play a role in the polarity, proliferation and migration of endothelial cells
- Selectively promotes FGF-induced MAPK activation through SRC.