PIPA5120588

ATP8B3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5120588-Each-of-1 In Stock ₹ 44,811.50

PIPA5120588 - Each of 1

₹ 44,811.50

In Stock

Quantity

1

Base Price: ₹ 44,811.50

GST (18%): ₹ 8,066.07

Total Price: ₹ 52,877.57

Antigen

ATP8B3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATP8B3

Gene Alias

aminophospholipid translocase ATP8B3; ATP1K; ATP8B3; ATPase class I type 8B member 3; ATPase phospholipid transporting 8B3; ATPase, aminophospholipid transporter, class I, type 8B, member 3; ATPase, class I, type 8B, member 3; ATPIK; FOS37502_2; Phospholipid-transporting ATPase IK; potential phospholipid-transporting ATPase IK; probable phospholipid-transporting ATPase IK

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

148229

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

2.35 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

O60423

Gene Symbols

ATP8B3

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human ATP8B3 (NP_620168.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Positive test controls include: HCT116
  • Immunogen sequence: VTAARNFGYV FLSRTQDTVT IMELGEERVY QVLAIMDFNS TRKRMSVLVR KPEGAICLYT KGADTVIFER LHRRGAMEFA TEEALAAFAQ ETLRTLCLAY REVAEDIYED WQQRHQEASL LLQNRAQALQ QLLGATAIED RLQDGVPETI KCLKKSNIKI WVLTGDKQET AVNIGFACEL LSENMLILEE KEISRILETY WENSNNLLTR ESLSQVKLAL VINGDFLDKL LVSLRKEPRA LAQNVNMDEA WQELGQSRRD FLYARRLSLL CRRFGLPLAA PPAQDSRARR SSEVLQERAF V P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids
  • Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules
  • May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes
  • Involved in acrosome reactions and binding of spermatozoa to zona pellucida.