PIPA596330

APRT Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA596330-Each-of-1 In Stock ₹ 46,502.50

PIPA596330 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

APRT

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Aprt

Gene Alias

adenine phosphoribosyl transferase, adenine phosphoribosyltransferase, AMP, AMP diphosphorylase, AMP pyrophosphorylase, APRT, APRTD, C85684, DKFZp686D13177, MGC125856, MGC125857, MGC129961, transphosphoribosidase

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11821, 353

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.67 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P07741, P08030

Gene Symbols

Aprt

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT (NP_0004761)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MADSELQLVE QRIRSFPDFP TPGVVFRDIS PVLKDPASFR AAIGLLARHL KATHGGRIDY IAGLDSRGFL FGPSLAQELG LGCVLIRKRG KLPGPTLWAS YSLEYGKAEL EIQKDALEPG QRVVVVDDLL ATGGTMNAAC ELLGRLQAEV LECVSLVELT SLKGREKLAP VPFFSLLQYE; Positive Samples: MCF7, 22Rv1, THP-1, A-549, K-562, HeLa, Mouse intestine; Cellular Location: Cytoplasm Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family
  • A conserved feature of this gene is the distribution of CpG dinucleotides
  • This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP)
  • It also produces adenine as a by-product of the polyamine biosynthesis pathway
  • A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis
  • Two transcript variants encoding different isoforms have been found for this gene.